Cerebellar function during development. Eyeblink conditioning, prism adaptation and interval production in children and adults.
Författare
Summary, in English
The performance on all tasks improved with age during childhood, and there were only weak and unclear associations between the tasks. Further, the duration of the interstimulus interval had effect on the learning during eyeblink conditioning, and there were sex differences in the performance among both children and adults. The findings suggest that there might be different underlying neural mechanisms involved during the three tasks, and that other factors, including cognitive, contribute to the performance. Eyeblink conditioning, prism adaptation, and finger tapping do not seem to reflect one homogeneous cerebellar function and can therefore not replace each other. Together these three tasks may contribute to a more complete picture of cerebellar function, and by extension, cerebellar dysfunction. The project highlights the importance of continuing to explore test parameters and maturational effects on cerebellar-dependent tasks during development. In the future, more knowledge about this and the underlying mechanisms may allow for refined methods investigating cerebellar dysfunction in neurodevelopmental disorders.
Avdelning/ar
Publiceringsår
2020
Språk
Engelska
Publikation/Tidskrift/Serie
Lund University, Faculty of Medicine Doctoral Dissertation Series
Issue
2020:7
Fulltext
Dokumenttyp
Doktorsavhandling
Förlag
Lund University, Faculty of Medicine
Ämne
- Neurosciences
Nyckelord
- Cerebellum
- Eyeblink conditioning
- Prism adaptation
- Finger tapping
- Development
- Children
- Adults
- Cerebellar function
- Neurodevelopmental disorders
- Cognitive disorders
Status
Published
Forskningsgrupp
- Communication and Cognition
- Associative Learning
ISBN/ISSN/Övrigt
- ISSN: 1652-8220
- ISBN: 978-91-7619-867-4
Försvarsdatum
29 januari 2020
Försvarstid
13:15
Försvarsplats
Segerfalksalen, BMC A10, Sölvegatan 17 i Lund
Opponent
- Dagmar Timmann (professor)